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I understand your question QM/GR. But there is also the simpler problem: how to make sense of QM and SR in the same consistent framework. Up to now, QM and Special Relativity cannot be considered in the same framework since QM is not local (at least this is the general opinion). At the moment there are not many proposals for the local QM. One of them is the Consistent History approach and another is the modified QM which I have proposed in the section nonlocality and relativity. At each case there is a preliminary problem of QM/SR before looking at the QM/GR problem.